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Archive | Gut Health and Food Safety Programme

ALL stories relating to the GHFS programme (these will also be displayed within the GHFS website)

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ME/CFS talks held in Norwich

An event held in Norwich in January 2017 gave the public a chance to hear about some of the biomedical research being undertaken on the debilitating condition ME (Myalgic Encephalomyelitis). The event was hosted by IFR and Invest in ME Research, a charity promoting biomedical research and education into ME, which is aiming to establish a […]

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Bifidobacterium breve. Image by K.R.Hughes

New evidence of how gut microbes affect Inflammatory Bowel Disease

Scientists at the Institute of Food Research (IFR) have uncovered a new mechanism linking bacteria in the gut to Inflammatory Bowel Disease (IBD). They have found that certain bacteria release molecules that interact with the lining of the gut to influence a process known as epithelial cell shedding. This shedding process is vital to maintaining […]

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omnipath

Omnipath sends strong signal

Combining the power of 27 data resources, Omnipath [http://omnipathdb.org] helps researchers see biological signalling pathways with unprecedented accuracy. Developed by researchers in the UK and Germany and published in Nature Methods, OmniPath offers a comprehensive, unified collection of literature-curated signalling pathways based on an analysis of 41 000 scientific papers. All the functions happening in […]

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Clostridium botulinum

Diversity in C. botulinum germination

A new study from the Institute of Food Research has filled a gap in our knowledge of germination of Clostridium botulinum, one of the most dangerous causes of food poisoning. C. botulinum bacteria produce a highly potent neurotoxin that if present in the body causes botulism, which often leads to paralysis and sometimes death. The […]

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Prof. Arjan Narbad, Dr Dr Ngozi Elumogo (NNUH) and Dr Lee Kellingray (IFR)

Norfolk hospital and science partnership cure patients of debilitating gut infection

A treatment programme for Clostridium difficile (C.diff) is being announced during International Infection Prevention Awareness Week 17-21 October. In the last year, the lives of 20 patients diagnosed with C. diff, a bacterium that infects the gut, have been transformed by the Norfolk and Norwich University Hospital by the use of Faecal Microbiota Transplant (FMT).  […]

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burgers

New technique to beat the food fraudsters

Shoppers can be more confident that their burgers are the real deal following a new method of testing for meat fraud developed at the Institute of Food Research on the Norwich Research Park. Exploiting subtle differences in a key meat protein, the addition of just 1% of horse into a beef burger or of beef […]

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EHEC t ileum oil-1_620

Little gut reaction to enterohaemorrhagic E. coli

A recently published study has found some evidence that enterohaemorrhagic E.coli(EHEC) may be able to evade or suppress our immune system. EHEC (aka E. coli O157) causes around 1200 cases of food poisoning in the UK every year. Symptoms are serious, ranging from diarrhoea to acute kidney failure and neurological damage. Outbreaks can be hard […]

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JCM

Do the Answers to ME/CFS lie within our Gut?

Researchers on the Norwich Research Park have published a review of evidence for a role of the gut microbiota and virome in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Commonly presenting with hugely diverse and debilitating symptoms including post-exertional tiredness, unrefreshing sleep, concentration problems and widespread pain, ME/CFS is very difficult to diagnose and treat. The disease affects […]

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chenweirichardmithen_240

UK-China Joint Centre for Probiotics Research

The Institute of Food Research and Jiangnan University have collaborated to initiate a UK-China Joint Centre for Probiotic Research. The centre builds on long term collaboration between Professor Chen Wei, at Jiangnan University, and Professor Arjan Narbad at the IFR, which receives strategic funding from the Biotechnology and Biological Sciences Research Council (BBSRC). After several […]

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RobKingsley1

Microevolution key to Salmonella’s success

Research led by Dr Rob Kingsley from the Institute of Food Research has shown how Salmonella rapidly “microevolves” during an epidemic. It highlights how whole genome sequencing is important in tracking pathogenic bacteria. Salmonella are one of the most common causes of bacterial disease in humans and animals. Part of their success comes from their […]

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L reuteri mucus copy_250

How probiotic protects against pathogen infection in the gut

A collaborative study by researchers on the Norwich Research Park has indicated how certain probiotic bacteria can help reduce infection by pathogenic E. coli. Previous clinical studies have suggested that certain probiotic bacteria could prevent pathogenic bacteria from infecting the human gut. In particular, one common type of bacteria found naturally in our gut, the […]

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Clostridium botulinum and its spore (inset) 
Jason Brunt, Kathryn Cross and Mary Parker

Discovery of mechanism for transfer of botulinum neurotoxin genes

A new study has shown how Clostridium botulinum could potentially transfer their deadly neurotoxin genes to other bacteria. This highlights the need for constant vigilance in identifying new threats to food safety. The botulinum neurotoxin is the most potent known, and has been much studied because of this, helping ensure it doesn’t get into our […]

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